The Cancer Letter

Inside information on cancer research and drug development

Harold Varmus reflects on the life of John Edward Porter, a House appropriator—and his friend
Porter helped orchestrate the doubling of the NIH budget between 1998 and 2003

In Brief

Alex A. Adjei named chair of Cleveland Clinic Taussig Cancer Institute
Joe W. Ramos named director of Louisiana Cancer Research Center
McKesson, HCA Healthcare to form oncology research joint venture
ESOP-ECO survey reveals cancer drug shortages in countries surrounding Ukraine
Dana-Farber establishes Lubin Family Foundation Scholar Awards
“Cecilie,” statue of a woman with incurable breast cancer, unveiled in Norway

Drugs & Targets

FDA grants accelerated approval to Tafinlar + Mekinist in unresectable or metastatic solid tumors with BRAF V600E mutation
FDA grants Fast Track designation to IK-930 in unresectable NF2-deficient mesothelioma
Cullinan Oncology, Taiho Pharmaceuticals complete agreement to develop and commercialize CLN-081/TAS6417
FDA orders JUUL products removed from U.S. markets
SomaLogic, OncoHost announce license agreement for the development of precision cancer diagnostics
MD Anderson, Invectys, CTMC announce strategic collaboration for CAR T-cell therapy development

In The Clinic

Trials & Tribulations

Transforming the future of radiation oncology:
Three ways collaboration accelerates FLASH radiation therapy research

Transforming the future of radiation oncology: Three ways collaboration accelerates FLASH radiation therapy research
ANCHOR trial shows that treatment of anal high-grade squamous intraepithelial lesions prevents anal cancer in people with HIV Three ways collaboration accelerates FLASH radiation therapy research
Trials & Tribulations
In early results “unprecedented in rectal cancer,” 14/14 patients show clinical complete response to dostarlimab
Oncologists, advocates, FDA call for an end to MTD and the “more is better” era in cancer drug dosing
Here’s how we can make clinical trials more inclusive
Trials & Tribulations

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The Cancer Letter is an independent weekly news publication and the leading source for information on the issues that shape oncology.

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