Issue 2 - Jan. 15, 2021
Issue 1 - Jan. 8, 2021
  • Guest Editorial

    Paskett: A three-time cancer survivor should not get COVID-19, but I did

    Cancer patients and survivors should not get COVID-19. A three-time cancer survivor should definitely not get COVID. But I did. And it was not good. Here is my story and the lessons I learned that might be of value to others.

  • Letter from the Editor & Publisher

    Presenting the Cancer History Project

    Historical documents have a way of vanishing. Manuscripts, letters, and photographs end up in city dumps. Memories become less granular, insight is lost. The documents that do get preserved often require a trip to the archives.

  • Cancer groups urge CDC to prioritize cancer patients for COVID-19 vaccination

    The American Cancer Society and the Association of Clinical Oncology are calling on the Centers for Disease Control and Prevention to give cancer patients a higher priority amid the rollout of vaccines against SARS-CoV-2.

  • Top 25 stories of 2020

    The year 2020 was, by any reckoning, one that most of us would prefer to relegate to history books—fun to read about, and hopefully not condemned to repeat.

  • Mace Rothenberg steps down as Pfizer CMO, replaced by Stanford’s Aida Habtezion

    Mace Rothenberg has stepped down as chief medical officer at Pfizer. His successor is Aida Habtezion, a Stanford researcher whose work is focused on leukocyte recruitment and immune responses in diseases affecting the digestive organs. 

  • In Brief

    • Welela Tereffe named chief medical executive at MD Anderson
    • Adam Marcus named interim executive director of Winship Cancer Institute of Emory University
    • Angela L. Talton named first chief diversity, equity and inclusion officer at City of Hope
    • Kashyap Patel elected president of COA
    • Steven Lemery named acting associate director of Tissue Agnostic Drug Development at FDA’s OCE
    • Roy Herbst, Worta McCaskill-Stevens, and Lawrence Shulman receives 2020 ACCC awards
    • Kristin Ferguson named senior director of ACCC
    • Melissa Johnson named program director of lung cancer research at Sarah Cannon
    • John Ryan named senior vice president and general counsel at Dana-Farber
    • Rutgers Cancer Institute of New Jersey receives $25 million for Cancer Immunology and Metabolism Center of Excellence
    • SU2C receives $10 million Exact Sciences grant for colorectal cancer screening and prevention initiative
    • Northwell opens $6.2 million cancer center in Riverhead NY
    • Mark Foundation awards five grants to accelerate a new class of cancer drugs based on induced proximity
    • National Association for Proton Therapy establishes Physician Advisory Committee
    • U.S. government passes law honoring legacy of Henrietta Lacks by increasing access to clinical trials
    • Massachusetts health care law expected to improve access to clinical trials
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  • Clinical Roundup

    • Study: Striking differences seen in COVID-19 responses in cancer patients
    • American College of Surgeons study reports drop in lung cancer screening, rise in malignancy rates during spring COVID-19 surge
    • Largest, most diverse ever study of prostate cancer genetics brings disparities into focus
    • New NCCN resource for survivors helps guide life after cancer diagnosis and treatment
    • Triple chemotherapy combination improves metastatic colorectal cancer outcomes
    • Miami Cancer Institute launches new and expanded clinical trials for COVID-19 treatments
    • Phase III Keytruda + Lenvima study shows improved OS, PFS in advanced endometrial cancer
    • Cabometyx significantly improved PFS in phase III trial of previously treated radioiodine-refractory differentiated thyroid cancer
    • Ohio State launches statewide study focused on breast cancer in Black women
    • Roswell Park researchers: Aggressive breast cancers in Black patients are related to immune factors
    • UCLA study: More women embracing ‘going flat’ after mastectomy
    • New combination therapy could help fight difficult-to-treat cancers with common mutations
  • Drugs & Targets

    • Tagrisso receives FDA approval as adjuvant therapy for NSCLC with EGFR mutations
    • Iclusig receives FDA sNDA approval for adult patients with resistant or intolerant chronic-phase CML
    • Xpovio receives FDA approval for refractory or relapsed multiple myeloma
    • Orgovyx receives FDA approval for advanced prostate cancer
    • Margenza receives FDA approval for metastatic HER2-positive breast cancer
    • CPI-613 receives FDA Fast Track Designation for treatment of AML
    • EU CHMP issues positive opinion for Keytruda as first-line treatment in adult patients in colorectal cancer indication
    • Bayer and Veracyte collaborate on precision oncology in thyroid cancer
    • Servier to acquire Agios Pharmaceuticals’ oncology business
    • Kite and Oxford BioTherapeutics establish cell therapy research collaboration in blood cancers and solid tumors
  • NCI Trials

    NCI Trials for Jan. 2021

    The National Cancer Institute approved the following clinical research studies last month. 

Issue 46 - Dec. 11, 2020
  • Conversation with The Cancer Letter

    Patrick Hwu on the challenge of making Moffitt the “cell therapy capital of the universe”

    Patrick Hwu, the new president and CEO of H. Lee Moffitt Cancer Center, is stepping in at a crucial turning point for the Tampa-based hospital.

  • Guest Editorial

    The Doctors’ Plot American style:

    President Donald Trump is hardly the first septuagenarian world leader to mistrust doctors and science.

  • BSA endorses Frederick Lab’s affiliation with NCI as  recompetition of $500M 10-year contract nears

    In a first procedural move of its kind, NCI asked its Board of Scientific Advisors to endorse the institute’s continuing affiliation with the Frederick National Laboratory for Cancer Research, a Federally Funded Research and Development Center.

  • NCI BSA approves 10 new and reissued concepts

    The NCI Board of Scientific Advisors has approved 10 new and reissued concepts.

    NCI also asked BSA to endorse recompetition of the institute’s contract with the Frederick National Laboratory for Cancer Research.

  • Cancer and industry groups file legal challenges to administration’s MFN rule

    Pharmaceutical and biotechnology industry groups, joined by cancer groups, filed legal challenges to an HHS rule that uses international reference prices to lower Medicare Part B prices.

  • In Brief

    • Stephanie Halene named chief of hematology at Yale Cancer Center and Smilow Cancer Hospital
    • Haggstrom named director of Regenstrief Institute Center for Health Services Research
    • Sue S. Yom named editor-in-chief of the International Journal of Radiation Oncology, Biology, Physics
    • DFCI and the Jimmy Fund receive $50 million donation from Pan-Mass Challenge
    • Smilow Cancer Hospital receives $135,000 CT Lions Eye Research Foundation grant to study eye cancer
    • Friends of Cancer Research forms new HRD Harmonization Project to create consistency in HRD use
    • Jack Evjy, Chang Oh Turkmani, Elizabeth Fago appointed to NCAB
  • Funding Opportunities

    DoD Ovarian Cancer Research Program Anticipated Funding Opportunities for Fiscal Year 2021

    Although FY21 funds have not been appropriated for the Department of Defense Ovarian Cancer Research Program, the OCRP is providing the information in this pre-announcement to allow investigators time to plan and develop ideas for submission to the anticipated FY21 funding opportunities.

  • TCCL Logo

  • Clinical Roundup

    • Some postmenopausal women with common breast cancer may forgo chemotherapy
    • Mindfulness meditation, survivorship classes reduce symptoms of depression in younger breast cancer survivors
    • ASCO issues comprehensive recommendations to strengthen cancer care and research during the COVID-19 pandemic
    • Studies reveal potential weaknesses in SARS-CoV-2 infection
    • City of Hope has developed a cancer-killing virus that activates immune system and helps eliminate colon cancer
  • Drugs & Targets

    • FDA issues a guidance on quality standards of the Mammography Quality Standards Act during COVID-19
    • Amgen and McKesson collaborate to advance cancer innovation in communities